Product Description

DMBT1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32015-50, RA32015-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: deleted in malignant brain tumors 1 (DMBT1) Homo sapiens Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC-p, IF (paraffin section)

Clonality: Polyclonal

Dilution: IHC-p 1:50-300

Molecular Weight: 265

Protein Molecular Weight (kDa): 265

Storage: -20°C/1 year

Human Gene ID: 1755

Human SwissProt Number: Q9UGM3

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only