Product Description

DMGDH Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61706-50, BS61706-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: DMGDH (dimethylglycine dehydrogenase), also known as ME2GLYDH or DMGDHD, is an 866 amino acid mitochondrial protein that plays a role in choline catabolism by catalyzing the demethylation of dimethylglycine to form sarcosine. Existing as a monomer that belongs to the gcvT family, DMGDH utilizes flavin adenine dinucleotide (FAD) and folate as cofactors. DMGDH is encoded by a gene that maps to human chromosome 5q14.1, defects of which are the cause of DMGDH deficiency (DMGDHD). Patients with DMGDHD experience muscle fatigue, have a fish-like odor and excrete an elevated level of N, N-dimethylglycine (DMG) in urine.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH, DMGDH

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 810-860 of Human DMGDH.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: DMGDH polyclonal antibody detects endogenous levels of DMGDH protein.

Molecular Weight: ~ 96 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UI17

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only