DMGDH rabbit pAb - ES2179

DMGDH rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2179-50, ES2179-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Alternate Name: DMGDH; Dimethylglycine dehydrogenase; mitochondrial; ME2GLYDH

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human DMGDH. AA range:817-866

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 97kD

Human Gene ID: 29958

Human SWISS Prot NO: Q9UI17

Subcellular Location: Mitochondrion.

Research Use Only