DNA Ligase III/LIG3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1887-20, A1887-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 113kDa
Observed Molecular Weight: 113kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 3980
SWISS: P49916
Alternate Names: LIG2; MTDPS20; LIG3alpha; DNA Ligase III/LIG3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling.
NCBI Alias: LIG3
Research Use Only