DNA topoisomerase I (TOP1) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12524-20, A12524-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IP, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 91kDa
Observed Molecular Weight: 120kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 7150
SWISS: P11387
Alternate Names: TOPI; DNA topoisomerase I (TOP1)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cancer.
NCBI Alias: TOP1
Research Use Only