DNAJC2/MPP11 (Phospho-Ser47) Rabbit Polyclonal Antibody - BT-AP09271

DNAJC2/MPP11 (Phospho-Ser47) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09271-20, BT-AP09271-50, BT-AP09271-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes| acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also| chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

Research Areas: Cancer; Signal transduction

Target Protein: DNAJC2

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: DNAJC2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q99543; Mouse: P54103; Rat: Q7TQ20

Synonyms: DNAJC2/MPP11;Ser47; DnaJ homolog subfamily C member 2; M-phase phosphoprotein 11; Zuotin-related factor 1

GeneID: Human: 27000; Mouse: 22791; Rat: 116456

Research Use Only