DNAJC2/MPP11 (phospho-Ser47) Rabbit Polyclonal Antibody - RA24263

DNAJC2/MPP11 (phospho-Ser47) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24263-50, RA24263-100

Citations, Manuals and MSDS Available upon request.

Background: DnaJ heat shock protein family (Hsp40) member C2 (DNAJC2) Homo sapiens This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 27000

Protein MW (KDa): 68

SWISS: Q99543

Source: Rabbit

Research Use Only