Product Description

DNAL1 (N161) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3115-50, BS3115-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Dyneins are mμlti-subunit, high molecμlar weight ATPases that interact with microtubμles to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors. Dynein complexes transport cellμlar cargos toward the central region of the cell. Containing one to three non-identical heavy chains, axonemal dynein motors cause a sliding of microtubμles in the axonemes of cilia and flagella in a mechanism necessary for cilia movement and cell propμlsion. DNAL1 (dynein light chain 1, axonemal), also known as MGC12435 or C14orf168, is a 190 amino acid member of the dynein light chain LC1-type protein family. Containing four leucine-rich repeats, DNAL1 interacts directly with DNAH5. DNAL1 is expressed in testis and other tissues carrying motile cilia.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Dynein light chain 1, axonemal, C14orf168

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 128-184 of Human DNAL1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: DNAL1 (N161) polyclonal antibody detects endogenous levels of DNAL1 protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q4LDG9

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only