Product Description

DNAL1 (N161) Polyclonal Antibody

Catalogue Numbers: BS3115-50, BS3115-100

Sizes: 50µl, 100µl

Alternative Name: Dynein light chain 1; axonemal; C14orf168

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q4LDG9

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors. Dynein complexes transport cellular cargos toward the central region of the cell. Containing one to three non-identical heavy chains, axonemal dynein motors cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia movement and cell propulsion. DNAL1 (dynein light chain 1, axonemal), also known as MGC12435 or C14orf168, is a 190 amino acid member of the dynein light chain LC1-type protein family. Containing four leucine-rich repeats, DNAL1 interacts directly with DNAH5. DNAL1 is expressed in testis and other tissues carrying motile cilia.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DNAL1 (N161) polyclonal antibody detects endogenous levels of DNAL1 protein.

Bioworld Molecular Weight: ~ 22 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of DNAL1 (N161) pAb at 1:1000 dilution
Lane 1: L02 whole cell lysate(20ug)
Lane 2: HepG2 whole cell lysate(40ug)
Lane 3: AML-12 whole cell lysate(40ug)
Lane 4: C6 whole cell lysate(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 128-184 of Human DNAL1.

Conjugate: Unconjugated

Modification: Unmodified