Product Description

DNase II Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65579-50, BS65579-100

Swiss-Prot: O00115

Host: Rabbit

DNase II Polyclonal Antibody-BS65579

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

Applications: WB,

All Applications: WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

Background: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

Purification and Purity: affinity purified by Protein A

Specificity: DNase II polyclonal Antibody detects endogenous levels of DNase II protein.

Bioworld Molecular Weight: ~45kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Anti-DNase II at 1/300 dilution, Anti-DNase II at 1/1000 dilution

Alternative Name: Acid DNase; Deoxyribonuclease 2 alpha; Deoxyribonuclease 2; Deoxyribonuclease II alpha; Deoxyribonuclease II; Deoxyribonuclease II lysosomal; Deoxyribonuclease-2-alpha; Deoxyribonuclease2; DeoxyribonucleaseII; DNASE 2; DNASE 2A; DNase II alpha; DNase II lysosomal; DNASE2; DNASE2A; DNaseII; DNL 2; DNL; DNL2; DNS2A_HUMAN; Lysosomal DNase II; R31240 2; R31240_2.

Immunogen: KLH conjugated synthetic peptide derived from human DNase II:201-300/360

Modification: Unmodified

Conjugate: Unconjugated