Product Description

DNM1L Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS7390-50, BS7390-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O00429

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB: 1:1000~1:3000
IF: 1:50~1:200

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DNM1L polyclonal antibody detects endogenous levels of DNM1L protein.

Bioworld Molecular Weight: ~82 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of A549 cells, using DRP1 antibody at 1:1000 dilution., Western blot analysis of extracts of various cell lines, using DRP1 antibody at 1:500 dilution., Immunofluorescence analysis of NIH/3T3 cells using DRP1 pAb at dilution of 1:50 (40x lens).

Alternative Name: DNM1L; DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV

Immunogen: Recombinant protein of human DRP1.

Conjugate: Unconjugated

Modification: Unmodified