DNMT1 Polyclonal Antibody-BS7606

DNMT1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS7606-50, BS7606-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P26358

Host: Rabbit

Reactivity: Human

Applications: WB, IF/ICC, IP

All Applications: WB,1:500 - 1:2000 | IF/ICC,1:50 - 1:200 | IP,1:50 - 1:100

Background: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Polyclonal Antibodies

Bioworld Molecular Weight: 200kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunoprecipitation analysis of 200ug extracts of 293T cells using 3ug DNMT1 antibody. Western Blot was performed from the immunoprecipitate using DNMT1 antibody at a dilution of 1:1000.

Alternative Name: ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNMT1

Immunogen: Recombinant fusion protein of human DNMT1(NP_001370.1).

Conjugate: Unconjugated

Modification: Unmodified