DOCK 180 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24283-50, RA24283-100
Citations, Manuals and MSDS Available upon request.
Background: dedicator of cytokinesis 1 (DOCK1) Homo sapiens This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: DOCK1; Dedicator of cytokinesis protein 1; 180 kDa protein downstream of CRK; DOCK180
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 1793
Protein MW (KDa): 215
SWISS: Q14185
Source: Rabbit
Research Use Only