DOCK 180 rabbit pAb - ES5015

DOCK 180 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5015-50, ES5015-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],

Alternate Name: DOCK1; Dedicator of cytokinesis protein 1; 180 kDa protein downstream of CRK; DOCK180

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 215kD

Human Gene ID: 1793

Human SWISS Prot NO: Q14185

Subcellular Location: Cytoplasm. Membrane. Recruited to membranes via its interaction with phosphatidylinositol 3, 4, 5-trisphosphate.

Research Use Only