DOCK 2 rabbit pAb - ES5016

DOCK 2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5016-50, ES5016-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016],

Alternate Name: DOCK2; KIAA0209; Dedicator of cytokinesis protein 2

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: WB 1:500-2000, Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from the Internal region of human DOCK 2.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 1794

Human SWISS Prot NO: Q92608

Subcellular Location: Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. Colocalizes with F-actin.

Research Use Only