DOCK4 rabbit pAb - ES16916

DOCK4 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES16916-50, ES16916-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human DOCK4 AA range: 533-583

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 9732

Human SWISS Prot NO: Q8N1I0

Subcellular Location: Cell membrane. Cell projection. Cytoplasm, cytosol. Colocalizes with EPHA2, RHOG and CTTN/cortactin at the tip of protrusions in migrating cells.

Research Use Only