Product Description

DOHH Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10846-50, MB10846-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9BU89

Host: Rabbit

Reactivity: Human

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Catalyzes the hydroxylation of the N6-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine (PubMed:16533814, PubMed:16371467, PubMed:19706422). Hypusination is unique to mature eIF-5A factor and is essential for its function .

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of DOHH in K562, HelaLysates using DOHH antibody.

Bioworld Molecular Weight: Calculated MW: 33 kDa; Observed MW: 33 kDa

Specificity: IgG

Alternative Name: HLRC1; hDOHH

Immunogen: A synthetic peptide of human DOHH

Conjugate: Unconjugated

Modification: Unmodified