Dok-2 (phospho Tyr299) rabbit pAb - ES1299

Dok-2 (phospho Tyr299) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1299-50, ES1299-100

Citations, Manuals and MSDS Available upon request.

Background: docking protein 2 (DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],

Alternate Name: DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56 (dok-2)

Source: Rabbit

Applications: WB; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human p56 Dok-2 around the phosphorylation site of Tyr299. AA range:266-315

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 48kD

Human Gene ID: 9046

Human SWISS Prot NO: O60496

Subcellular Location: cytosol,

Research Use Only