Dopamine D3 receptor Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS65798-50, BS65798-100 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Swiss-Prot: P30728 Host: Rabbit Reactivity: Human, Mouse, Rat, Applications: WB, IHC-P All Applications: WB=1:500-2000 IHC-P=1:100-500 Background: This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is expressed in phylogenetically older regions of the brain, suggesting that it plays a role in cognitive and emotional functions. It is a target for drugs which treat schizophrenia, drug addiction, and Parkinson disease. Alternative splicing of this gene results in multiple transcript variants that would encode different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). Also known as: dopamine D3 receptor; 3 dopamine receptor; D; Dopamine receptor D3; DRD; ETM1; FET1. Purification and Purity: affinity purified by Protein A Storage and Stability: Store at 4°C short term. Aliquot and store at -29°C long term. Avoid freeze-thaw cycles. Specificity: Dopamine D3 receptor Polyclonal Antibody detects endogenous levels of Dopamine D3 receptor protein. Bioworld Molecular Weight: ~48 kDa Note: For research use only, not for use in diagnostic procedure. Extra Notes: Primary: Anti-Dopamine D3 receptor at 1/300 dilution, Primary: Anti-Dopamine D3 receptor at 1/300 dilution, Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Dopamine D3 receptor) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C Alternative Name: DRD3; 3dopamine receptor; D; Dopamine receptor D3; DRD3; Dopamine receptor 3; ETM1; FET1; D(3) dopamine receptor; DRD3; DRD3_HUMAN. Immunogen: KLH conjugated synthetic peptide derived from mouse DRD3:352-446/446 Conjugate: Unconjugated Modification: Unmodified