Dorfin Polyclonal Antibody - BT-AP02706

Dorfin Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02706-20, BT-AP02706-50, BT-AP02706-100

Citations, Manuals and MSDS Available upon request.

Background: RNF19A encodes a member of the ring between ring fingers (RBR) protein family, and the ring finger protein 19A, RBR E3 ubiquitin protein ligase contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants.

Research Areas: Neuroscience

Target Protein: RNF19A

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Dorfin Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 90696

UniProt Accession: Human: Q9NV58; Mouse: P50636

Synonyms: RNF19A; RNF19; E3 ubiquitin-protein ligase RNF19A; Double ring-finger protein; Dorfin; RING finger protein 19A; p38

GeneID: Human: 25897; Mouse: 30945

Research Use Only