Doublecortin Monoclonal Antibody-MB10250

Doublecortin Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10250-50, MB10250-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O43602

Host: Rabbit

Reactivity: Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Mutations in Doublecortin cause Lissencephaly (smooth brain), a neuronal migration disorder characterized by epilepsy and mental retardation. Doublecortin is a microtubule associated protein that stabilizes and bundles microtubules. A conserved doublecortin domain mediates the interaction with microtubules, and interestingly most missense mutations cluster in this domain.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Doublecortin in rat BrainLysates using Doublecortin antibody.

Bioworld Molecular Weight: Calculated MW: 41 kDa; Observed MW: 41 kDa

Specificity: IgG

Alternative Name: DCX; DBCN; LISX; Neuronal migration protein doublecortin; Doublin; Lissencephalin-X; Lis-X

Immunogen: Recombinant protein of human Doublecortin

Conjugate: Unconjugated

Modification: Unmodified