Doublecortin Rabbit Monoclonal Antibody-MB66252

Doublecortin Rabbit Monoclonal Antibody

Catalogue Numbers: MB66252-50, MB66252-100

Sizes: 50µl, 100µl

Product: Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Swiss-Prot: Q9ESI7

Host: Rabbit

Reactivity: Rat

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May participate along with PAFAH1B1/LIS-1 in a distinct overlapping signaling pathway that promotes neuronal migration.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of Doublecortin protein.

Extra Notes: Western blot analysis of Doublecortin expression in rat brain (A) whole cell lysates.

Bioworld Molecular Weight: ~ 41 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: DBCN; LISX; Neuronal migration protein doublecortin; Doublin; Lissencephalin-X; Lis-X

Immunogen: Recombinant protein of human Doublecortin

Conjugate: Unconjugated

Modification: Unmodified