DPYD Polyclonal Antibody - RA24318

DPYD Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24318-50, RA24318-100

Citations, Manuals and MSDS Available upon request.

Background: dihydropyrimidine dehydrogenase (DPYD) Homo sapiens The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: DPYD; Dihydropyrimidine dehydrogenase [NADP (+) ]; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 1806

Protein MW (KDa): 120

SWISS: Q12882

Source: Rabbit

Research Use Only