DR4 Polyclonal Antibody - BT-AP02725

DR4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02725-20, BT-AP02725-50, BT-AP02725-100

Citations, Manuals and MSDS Available upon request.

Background: TNF receptor superfamily member 10a encoded by TNFRSF10A is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

Research Areas: Cell Biology

Target Protein: TNFRSF10A

Applications: WB, IF, ELISA

Reactivity: Human, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: DR4 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 50061

UniProt Accession: Human: O00220

Synonyms: TNFRSF10A; APO2; DR4; TRAILR1; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD antigen CD261

GeneID: Human: 8797

Research Use Only