DR5 Mouse Monoclonal Antibody - RA11100

DR5 Mouse Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11100-50, RA11100-100

Citations, Manuals and MSDS Available upon request.

Background: TNF receptor superfamily member 10b (TNFRSF10B) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; ICC

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 8795

Protein MW (KDa): 48

SWISS: O14763

Source: Mouse

Research Use Only