DR5/TRAILR2/TNFRSF10B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1236-20, A1236-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 48kDa
Observed Molecular Weight: 48kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 8795
SWISS: O14763
Alternate Names: DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; DR5/TRAILR2/TNFRSF10B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Growth factors, Death Receptor Signaling Pathway, Immunology Inflammation, CDs, NF-kB Signaling Pathway.
NCBI Alias: TNFRSF10B
Research Use Only