DR6 (Phospho-Ser562) Rabbit Polyclonal Antibody - BT-AP02307

DR6 (Phospho-Ser562) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02307-20, BT-AP02307-50, BT-AP02307-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1)| and induces cell apoptosis. Through its death domain| the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein| which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation| and may be involved in inflammation and immune regulation.

Research Areas: Cell biology

Target Protein: TNFRSF21

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: DR6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O75509; Mouse: Q9EPU5

Synonyms: DR6;Ser562; Tumor necrosis factor receptor superfamily member 21; Death receptor 6; CD antigen CD358

GeneID: Human: 27242; Mouse: 94185

Research Use Only