DRA rabbit pAb - ES4147

DRA rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4147-50, ES4147-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008],

Alternate Name: SLC26A3; DRA; Chloride anion exchanger; Down-regulated in adenoma; Protein DRA; Solute carrier family 26 member 3

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from the C-terminal region of human DRA.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 84kD

Human Gene ID: 1811

Human SWISS Prot NO: P40879

Subcellular Location: Apical cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Localized in sperm membranes. Midpiece of sperm tail. Colocalizes with CFTR at the midpiece of sperm tail (By similarity).

Research Use Only