DRD4 Polyclonal Antibody - E-AB-12360

DRD4 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-12360-60, E-AB-12360-120, E-AB-12360-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: DRD4

Target Synonym: D(2C) dopamine receptor; D(4) dopamine receptor (D(2C) dopamine receptor).; D(4) dopamine receptor; D4 dopamine receptor; D4DR; Dopamine D4 receptor; DRD 4; Drd4; DRD4

Research Areas: Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P21917

Background: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human DRD4

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150

Calculated MW: 48kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only