Product Description

DRP1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3161-50, MB3161-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O00429

Host: Mouse

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, FC

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100

Background: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 82 kDa; Observed MW: 82 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of DRP1 in PC-12, LNCAP and NIH/3T3 lysates using DRP1 antibody., Immunofluorescence analysis of DRP1 in Hela cells using DRP1 antibody. Blue: DRAQ5 fluorescent DNA dye., Flow cytometry analysis of HEK293 cells using DNM1L antibody and negative control.

Alternative Name: DNM1L; DLP1; DRP1; Dynamin-1-like protein; Dnm1p/Vps1p-like protein; DVLP; Dynamin family member proline-rich carboxyl-terminal domain less; Dymple; Dynamin-like protein; Dynamin-like protein 4; Dynamin-like protein IV; HdynIV; Dynamin-rela

Immunogen: Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.

Conjugate: Unconjugated

Modification: Unmodified