DRP1 Polyclonal Antibody - E-AB-67035

DRP1 Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-67035-60, E-AB-67035-120, E-AB-67035-200 Citations, Manuals and MSDS Available upon request. Abbreviation: DRP1 Target Synonym: DNM1L; DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV Research Areas: Cancer, Cell Biology, Metabolism, Neuroscience, Signal Transduction Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Mouse, Rat Application: WB, IF Isotype: IgG Clonality: Polyclonal UNIProt ID: O00429 Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. Concentration: 1mg/mL Immunogen: Recombinant protein of human DRP1 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Purification Method: Affinity purification Dilution: WB 1:500-1:2000 IF 1:50-1:200 Calculated MW: 60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa Observed MW: 82kDa Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only