Product Description

DSC2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS71520-50, BS71520-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q02487

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB 1:1000 - 1:2000

Background: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DSC2 polyclonal antibody detects endogenous levels of DSC2 protein.

Bioworld Molecular Weight: ~ 100 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extract of various cells, using DSC2 antibody.

Alternative Name: DG2; DSC3; CDHF2; ARVD11; DGII/III;

Immunogen: Recombinant protein of human DSC2

Conjugate: Unconjugated

Modification: Unmodified