Product Description

DSC3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32067-50, RA32067-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: desmocollin 3 (DSC3) Homo sapiens The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 98

Protein Molecular Weight (kDa): 98

Storage: -20°C/1 year

Human Gene ID: 1825

Human SwissProt Number: Q14574

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only