DSE Rabbit Polyclonal Antibody - RA32072

DSE Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32072-50, RA32072-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.249% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2)

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 29940

Protein MW (KDa): 105

SWISS: Q9UL01

Source: Rabbit

Research Use Only