Product Description

Dsg1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24336-50, RA24336-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: desmoglein 1 (DSG1) Homo sapiens This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: Desmoglein-1 (Cadherin family member 4;Desmosomal glycoprotein 1;DG1;DGI;Pemphigus foliaceus antigen)

Clonality: Polyclonal

Dilution: WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000

Molecular Weight: 160

Protein Molecular Weight (kDa): 160

Storage: -20°C/1 year

Human Gene ID: 1828

Human SwissProt Number: Q02413

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only