Dsg1 Polyclonal Antibody - RA24337

Dsg1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24337-50, RA24337-100

Citations, Manuals and MSDS Available upon request.

Background: desmoglein 1 (DSG1) Homo sapiens This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: DSG1; CDHF4; Desmoglein-1; Cadherin family member 4; Desmosomal glycoprotein 1; DG1; DGI; Pemphigus foliaceus antigen

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 1828

Protein MW (KDa): 114

SWISS: Q02413

Source: Rabbit

Research Use Only