Product Description

Dsg2 (V440) Polyclonal Antibody

Catalogue Numbers: BS3848-50, BS3848-100

Sizes: 50µl, 100µl

Alternative Name: Desmoglein 2; 1829; DSG2; 125671; Q14126; CDHF5; HDGC; MGC117034; MGC117036; MGC117037; ; Mouse monoclonal [3G132] to Desmoglein 2; 1829; DSG2; 125671; Q14126; CDHF5; HDGC; MGC117034; MGC117036; MGC117037; ; Desmoglein-2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q14126

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Dsg2 (V440) polyclonal antibody detects endogenous levels of Dsg2 protein.

Bioworld Molecular Weight: ~ 140 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Dsg2 (V440) pAb at 1:1000 dilution
Lane 1: Hela whole cell lysate(20ug)
Lane 2: The Embryo tissue lysate of Mouse(40ug)
Lane 3: SGC7901 whole cell lysate(40ug)
Lane 4: PC12 whole cell lysate(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 408-456 of Human Dsg2.

Conjugate: Unconjugated

Modification: Unmodified