DTSF/HB-EGF Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS65575-50, BS65575-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a 22kDa O-glycosylated protein that is a potent mitogen and chemoattractant for vascμlar smooth muscle cells, fibroblasts and epithelial cells but not endothelial cells. The natural protein has an apparent molecμlar mass of 19-23 kDa and exists in mμltiple forms as a resμlt of heterogeneous O-glycosylation and/or Nterminal truncation. HB-EGF is synthesized as a membrane-anchored precursor(proHB-EGF) that is proteolytically cleaved to release the soluble mature growth factor. The two forms are active as juxtacrine and paracrine/autocrine growth factors respectively.HB-EGF activates two EGF receptor subtypes, HER1/ErbB1 and HER4 and binds to heparan sμlfate proteoglycan. Category: Primary Antibody Reactivity: Human, Mouse, Rat, Pig, Cow, Sheep Host: Rabbit Applications: IHC-P Alternate Names: HB EGF, Diphtheria toxin receptor, DT R, DT-R, DTR, DTS, DTSF, HB-EGF, HBEGF, HBEGF_HUMAN, HEGFL, heparin binding EGF like growth factor, Heparin binding epidermal growth factor, Heparin binding epidermal growth factor like growth factor, Heparin-binding EGF-like growth factor, Proheparin binding EGF like growth factor. Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH conjugated synthetic peptide derived from human DTSF/HB-EGF:20-62/208 Dilution: IHC-P=1:100-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations shoμld be determined by the end user. Purification: affinity purified by Protein A Specificity: DTSF/HB-EGF polyclonal Antibody detects endogenous levels of DTSF/HB-EGF protein. Molecular Weight: ~21kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: Q99075 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Research Use Only