DTX2 Polyclonal Antibody-BS8881

DTX2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8881-50, BS8881-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q86UW9

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200

Background: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DTX2 polyclonal antibody detects endogenous levels of DTX2 protein.

Bioworld Molecular Weight: ~ 67kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cell lines, using DTX2 antibody.

Alternative Name: Probable E3 ubiquitin-protein ligase DTX2; Protein deltex-2; Deltex2; hDTX2; RING finger protein 58; DTX2; KIAA1528; RNF58

Immunogen: Recombinant full length Human DTX2.

Conjugate: Unconjugated

Modification: Unmodified