DTYMK Monoclonal Antibody-MB12004

DTYMK Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12004-50, MB12004-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P23919

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: DTYMK (deoxythymidylate kinase (thymidylate kinase)), also known as CDC8, TMPK, TYMK or dTMP kinase, is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 24 kDa; Observed MW: 24 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of DTYMK in Hela, Ramos lysates using DTYMK antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using DTYMK antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: CDC8; TMPK; TYMK; PP3731

Immunogen: A synthetic peptide of human DTYMK

Conjugate: Unconjugated

Modification: Unmodified