DTYMK Polyclonal Antibody-BS8520

DTYMK Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8520-50, BS8520-100

Swiss-Prot: P23919

Host: Rabbit

DTYMK Polyclonal Antibody-BS8520

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB 1:500 - 1:2000
IF 1:50 - 1:200

Background: DTYMK (deoxythymidylate kinase (thymidylate kinase)), also known as CDC8, TMPK, TYMK or dTMP kinase, is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: DTYMK polyclonal antibody detects endogenous levels of DTYMK protein.

Bioworld Molecular Weight: ~ 23kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using DTYMK antibody., Immunofluorescence analysis of A549 cell using DTYMK antibody. Blue: DAPI for nuclear staining.

Alternative Name: Thymidylate kinase; dTMP kinase; DTYMK; CDC8; TMPK; TYMK

Immunogen: Recombinant full length Human DTYMK.

Modification: Unmodified

Conjugate: Unconjugated