DU4L7 rabbit pAb - ES16882

DU4L7 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES16882-50, ES16882-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human DU4L7 AA range: 314-364

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human SWISS Prot NO: P0CJ90

Subcellular Location: Nucleus

Research Use Only