DU4L7 Rabbit Polyclonal Antibody - RA24344

DU4L7 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24344-50, RA24344-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD) . [provided by RefSeq, Jun 2014],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1：500-2000

Applications: WB

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 0

SWISS: P0CJ90

Source: Rabbit

Research Use Only