Product Description

DUSP10 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65743-50, BS65743-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimμli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellμlar stresses, thereby negatively regμlating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. MKP-5 preferentially binds to p38, but also to SAPK/JNK. It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus. MKP-5 has been implicated in cell proliferation and apoptosis, tumor invasion and immune responses.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit

Host: Rabbit

Applications: IHC-P

Alternate Names: MKP5, MKP 5, MKP-5, Dual specificity phosphatase 10, Dual specificity phosphatase MKP 5, Dual specificity phosphatase MKP5, Dual specificity protein phosphatase 10, DUS10_HUMAN, DUSP 10, DUSP10, DUSP10 protein, MAP kinase phosphatase 5, Mitogen activated protein kinase phosphatase 5, Mitogen-activated protein kinase phosphatase 5, Serine/threonine specific protein phosphatase.聽聽

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human DUSP10/MKP5:161-260/482

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: DUSP10 Polyclonal Antibody detects endogenous levels of DUSP10 protein.

Molecular Weight: 53kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Y6W6

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only