Product Description

DUSP19 (F133) Polyclonal Antibody

Catalogue Numbers: BS2336-50, BS2336-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q8WTR2

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB IHC IF

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200

Background: Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The stress-activated protein kinase (SAPK) pathway-regulating phosphatase 1 (SKRP1) binds to MAP kinase MKK-7 to regulate JNK.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DUSP19 (F133) polyclonal antibody detects endogenous levels of DUSP19 protein.

Extra Notes: Western blot (WB) analysis of DUSP19 (F133) pAb at 1:500 dilution
Lane1:Panc1 whole cell lysate(40ug)
Lane2:L02 whole cell lysate(40ug)
Lane3:H9C2 whole cell lysate(40ug)
Lane4:AML-12 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 28 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Dual specificity protein phosphatase 19; Dual specificity phosphatase TS-DSP1; Low molecular weight dual specificity phosphatase 3; LMW-DSP3; Protein phosphatase SKRP1; Stress-activated protein kinase pathway-regulating phosphatase 1; SAPK pathway-regulating phosphatase 1; DUSP17; LMWDSP3; SKRP1; DUSP19

Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human DUSP19.

Conjugate: Unconjugated

Modification: Unmodified