DYL1 Rabbit Polyclonal Antibody - RA24362

DYL1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24362-50, RA24362-100

Citations, Manuals and MSDS Available upon request.

Background: Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1：50-200

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 8655

SWISS: P63167

Source: Rabbit

Research Use Only