DYM rabbit pAb - ES16842

DYM rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES16842-50, ES16842-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein which is necessary for normal skeletal development and brain function. Mutations in this gene are associated with two types of recessive osteochondrodysplasia, Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia, which involve both skeletal defects and mental retardation. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human DYM AA range: 30-80

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 54808

Human SWISS Prot NO: Q7RTS9

Subcellular Location: Cytoplasm. Golgi apparatus. Membrane; Lipid-anchor. Sequence analysis programs clearly predict 1 transmembrane region. However, PubMed:18996921 shows that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol.

Research Use Only