Dynamin I (phospho Ser774) rabbit pAb - ES5010

Dynamin I (phospho Ser774) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5010-50, ES5010-100

Citations, Manuals and MSDS Available upon request.

Background: dynamin 1 (DNM1) Homo sapiens This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Alternate Name: DNM1; DNM; Dynamin-1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Dynamin-1 around the phosphorylation site of Ser774. AA range:740-789

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 97kD

Human Gene ID: 1759

Human SWISS Prot NO: Q05193

Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Microtubule-associated.

Research Use Only