Dyrk1B rabbit pAb - ES7970

Dyrk1B rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7970-50, ES7970-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],

Alternate Name: DYRK1B; MIRK; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Minibrain-related kinase; Mirk protein kinase

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human DYR1B. AA range:331-380

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 70kD

Human Gene ID: 9149

Human SWISS Prot NO: Q9Y463

Subcellular Location: Nucleus. Nucleus, nucleolus. Chromosome. Localizes to sites of double-strand breaks (DSBs) following DNA damage.

Research Use Only