DYRK2 Polyclonal Antibody-BS8646

DYRK2 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8646-50, BS8646-100

Swiss-Prot: Q92630

Host: Rabbit

DYRK2 Polyclonal Antibody-BS8646

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200
IF: 1:50~1:200

Background: DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: DYRK2 polyclonal antibody detects endogenous levels of DYRK2 protein.

Bioworld Molecular Weight: ~ 67kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using DYRK2 antibody., Immunofluorescence analysis of U20S cell using DYRK2 antibody. Blue: DAPI for nuclear staining.

Alternative Name: Dual specificity tyrosine-phosphorylation-regulated kinase 2; DYRK2

Immunogen: Recombinant full length Human DYRK2.

Modification: Unmodified

Conjugate: Unconjugated