Product Description

Dysferlin Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24378-50, RA24378-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: dysferlin (DYSF) Homo sapiens The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF/ICC, ELISA

Alternate Names: DYSF, FER1L1, Dysferlin, Dystrophy-associated fer-1-like protein, Fer-1-like protein 1

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight: 240

Protein Molecular Weight (kDa): 240

Storage: -20°C/1 year

Human Gene ID: 8291

Human SwissProt Number: O75923

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only